广州地区132对不明原因不孕夫妇抗精子抗体测定

Investigation of Antispermatozoal Antibodies from 132 Unexplained Infertile Couples from Guangzhou

对广州地区132对(264例)不明原因不孕夫妇,进行血清抗精子抗体测定,采用精子凝集试验(Sperm-agglutination test,SAT)和精子制动试验(Spermimmobilization test,SIT)方法。精子凝集试验有两种,即试管玻片凝集试验(Tube-Slide agglutination test,TSAT)及明胶凝集试验(Gelatin agglutination test,GAT)。试验同时与正常孕妇,未婚少女各132例及兔抗人精子血清做阴性和阳性对照。SAT(TSAT和GAT)试验结果有3.30％(4/132)男性患者及7.58％(10/132)女性患者为阳性。SIT试验有3.30％(4/132)男性患者与6.81％(9/132)女性患者为阳性。试验结果提示:对不明原因不孕患者有必要先排除由抗精子抗体这一免疫因素所引起的不孕。

132 unexplained infertile couples (264 cases) from Guangzhou were investigated by using sperm-agglutination test (SATT), including tube-slide agglutination test (TSAT) and gelatin-agglutination test (GAT), and sperm-immobilization test (SIT). The results showed that 3.03% of men (4/132) and 7.85% of women (10/132) were positive in both TSAT and GAT. 3.03% of men (4/132) and 6.81% of women (9/132) were positive in SIT. These data indicateed that it would be necessary for unexplained infertile couples to investigate their antispermatozoal antibodies.