摘要
目的:探索巴中产栀子的品质。方法:应用高效液相色谱仪和蒸发光散射检测器对栀子主要有效成分栀子苷、西红花苷Ⅰ、熊果酸进行含量测定,采用t检验和Z总分综合评价巴中产栀子的质量。结果:t检验结果表明,巴中产栀子中栀子苷含量显著高于湖北栀子(P<0.05),极显著高于江西或江津产栀子(P<0.001);巴中产栀子中西红花苷Ⅰ含量极显著高于湖北、江西或江津产栀子(P<0.001);巴中产栀子中熊果酸含量极显著高于湖北、江西或江津产栀子(P<0.001)。以主要有效成分栀子苷质量分数X1、西红花苷Ⅰ质量分数X2、熊果酸质量分数X3与综合评价Z总分建立三元线性回归方程:Z=-11.213 6+0.021 82X1+0.560 2X2+17.331 6X3(R=0.999 9);Z总分综合评价结果表明,巴中产栀子Z总分遥遥领先于湖北、江西或江津产栀子。结论:巴中产栀子的品质优异,值得政府和社会各界的广泛关注。
Objective: To explore quality of Gardeniae Fruetus from Bazhong. Method: HPLC and ELSD were used to determine the content of geniposide, croein I , and ursolie acid. Using t-test and Z-score comprehensive evaluation on quality of Gardeniae Fruetus from Bazhong. Result: Results of t- test showed that the content of Geniposide in Gardeniae Fructus from Bazhong is significantly higher than in Gardeniae Fructus from Hubei (P 〈 0. 05) , outstandingly higher than in Gardeniae Fructus from Jiangxi or Jiangjin (P 〈 0. 001 ) ; the content of crocin I and ursolic acid in Gardeniae Fructus from Bazhong was remarkablly higher than in Gardeniae Fructus from Hubei or Jiangxi or Jiangjin (P 〈 0. 001 ) ; we established multiple linear regression equation between Z-score and ratios of geniposide, crocin I , ursolic acid, geniposide X1, crocin I X2 and ursolic acid X3, respectively, the multiple linear regression equation was Z = - 11. 213 6 +0. 0218 2X1 +0. 560 2XE + 17. 331 6X3 (RE = 0. 999 9). Results of Z-score comprehensive evaluation showed that Z-score of Gardeniae Fructus from Bazhong is far ahead of Gardeniae Fructus from Hubei or Jiangxi or Jiangjin. Conclusion: Quality of Gardeniae Fructus from Bazhong is very good; Gardeniae Fructus from Bazhong is well worth focusing by government and society.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第24期115-119,共5页
Chinese Journal of Experimental Traditional Medical Formulae
基金
四川省2010年科技支撑计划项目(2010SZ0049)
四川省2011年科技支撑计划项目(2011SZ0048)
四川省教育厅重点科研项目(2005A071)
关键词
巴中产栀子
品质
主要有效成分
多指标综合评价
Gardeniae Fructus from Bazhong
quality
main active ingredients
multi-index comprehensive evaluation