中西医结合治疗早期糖尿病肾病34例

Combining Traditional Chinese and Western MedicineTreatment 34 Patients of Prophase Diabetic Nephropathy Clinical Research

目的:探讨中西医结合治疗早期糖尿病肾病的治疗效果。方法:选择2010年1月到2011年12月我院住院的71例早期糖尿病肾病患者,采用西医即口服卡托普利(25 mg/次,2次/d)和胰激肽原酶(240 U/次,3次/d)对症治疗37例为对照组,在西医治疗基础上加服自拟复方中药34例作为研究组。两组持续治疗12周。观察并比较两组的疗效,测定治疗前后尿素氮(BUN)、血肌酐(SCr),24 h尿蛋白定量的变化。结果:对照组的总有效率为82.8%,治疗组的总有效率为94.8%,两组相比,差异具有统计学意义(P<0.05);两组治疗后BUN,SCr,24 h尿蛋白定量降低均较明显,较治疗前相比差异具有统计学意义(P<0.05),与对照组比较,治疗组各指标的效果要明显优于对照组,差异显著,有统计学意义(P<0.05)。结论:中西医结合治疗糖尿病肾病的治疗效果显著,值得推广。

Objective： Explore combining traditional Chinese and western medicine treatment of prophase diabetic nephropathy therapy effect. Method： Selection in January 2010 to december 2011 in our hospital of 72 cases with prophase diabetic nephropathy, the western medicine that oral enalapril （25 mg, bid） and pancreatic enzyme （240 U, tid） symptomatic treatment of peptides 37 cases as control group, in western medicine treatment on the basis of traditional Chinese medicine to serve with the 34 patients in as a research group. The two groups have been treatmented for 12 weeks. Observe and compare the curative effect of two groups, the determination of the urea nitrogen （BUN） before and after, creatinine （SCr） , 24 h urine protein quantitative change. Result： The total effective rate of 82.8% in the control group, the total effective rate of 94.8% in the treatment group treatment of compared with the two groups, the statistically is significant difference （P 〈 0.05）; The two groups after treating BUN, SCr, 24 h urine protein quantitative obviously lower than that, there is statistically significant （P 〈 0.05）, compared with controls group , the effectiveness of the treatment group＇s each index is much better than control group, the difference was statistically significant （P 〈 0.05）. Conclusion： Combining traditional Chinese and western medicine treatment of diabetic nephropathy therapy effect significantly, which is worthy be popularized.