养血化瘀方治疗血瘀型先兆流产临床观察

Clinical observation of "Yangxue Huayu Decoction" in treating threatened abortion of blood stasis

目的观察养血化瘀方治疗血瘀型先兆流产的临床疗效。方法将63例病例随机分为两组,治疗组33例给予养血化瘀方口服,对照组30例采用传统益气养血补肾中药。两组均以7～10天为1个疗程,共治疗1～3个疗程;观察血清绒毛膜促性腺激素(HCG)、孕酮(P)含量的变化情况,超声观察胎心、孕囊等变化情况,并综合评价临床疗效。结果①治疗组、对照组总有效率分别为90.9%、70.0%;组间临床疗效比较,差异有统计学意义(P<0.05)。②组内比较,两组孕6周、7周、8周、9周血HCG水平较孕5周及本组前1周差异均有统计学意义(P<0.05,P<0.01),各孕周血P含量较孕5周及本组前1周差异均无统计学意义(P>0.05);两组间同期比较,孕7周、8周、9周血HCG水平差异有统计学意义(P<0.05,P<0.01),各孕周血P水平差异均无统计学意义(P>0.05)。结论养血化瘀方治疗血瘀型先兆流产疗效良好。

Objective To observe the clinical effect of ＂Yangxue Huayu Decoction＂ in the treatment of threatened abortion of blood stasis.Methods Sixty-three subjects were randomly divided into two groups： treatment group in which 33 cases were treated with ＂Yangxue Huayu Decoction＂ and control group in which 30 cases were treated with herbal prescription effective to supplement qi-blood and nourish kidney.The effect was evaluated by observing the levels of blood HCG and progesterone（P）,type B ultrasonic image,fetal heart rate and gestational sac.Results The effective rate was 90.9% in the treatment group,and 70.0% in the control group,with a significant difference between them（P0.05）.After treatment,blood HCG levels of 6-9 gestational weeks were increased gradually and higher than that of 5 gestational weeks（P0.05,P0.01）;blood P levels showed less correlation with time in early pregnancy in both groups（P0.05）.And during 7-9 gestational weeks,the blood HCG levels increased more significantly in treatment group than those in control group（P0.05,P0.01）,and there was no difference in blood P levels between the two groups（P0.05）.Conclusion ＂Yangxue Huayu Decoction＂ is quite effective for threatened abortion of blood stasis.