摘要
目的：测定Ｗｉｓｔａｒ大鼠丘脑外侧背核区（ＬＤ区）血流量正常值范围。方法：Ｗｉｓｔａｒ大鼠按性别和体重分４组。立体定向下将ＬＤＦ探头定位于双侧ＬＤ区。结果：１１９只大鼠共计２３８个ＬＤ区ＬＤＦ值为（８８±２７）ＰＵ．数据近似正态分布。不同性别组间、不同体重组间以及同一个体双侧ＬＤ区ＬＤＦ测量值均无显著性差别（Ｐ＞０．１０）。结论：Ｗｉｓｔａｒ大鼠ＬＤ区ＬＤＦ测量正常值范围为４４～１４３ＰＵ，不同实验样水间及同一个体双侧ＬＤ区ＬＤＦ监测可互为对照。
Aim: The study is employed to assess the fundamental characteristic of regional cerebral blood flow (rCBF) val- ue of LDF in the laterodorsal thalamus nucleus (LD) of Wistar rats, especially the range of normal value of them. Methods: All the 119 Wistar rats were divided into four groups,according to weight and sex. The needle probe was properly positioned into the LD region by using a small-radent stereotaxic instrument. Results:The mean rCBF value of LDF of 238 investigated LD region was 88±27PU. The test of normality (u test) demonstrated all the data approximately submitted normal distribu- tion. The difference in each group (different sex, weight and side)showed no statistical significance (P>0.10). Conclusion: The range of normal rCBF value of LDF in the LD region of Wistar rats is between 44PU and 143PU. The result could be used for work with animals of different sex,weight and side.
出处
《中国临床神经科学》
2000年第2期104-106,共3页
Chinese Journal of Clinical Neurosciences
