环境内分泌干扰物对母婴健康影响研究进展

Effects of Environmental Endocrine Disruptors on Mother and Child Health

在概述环境内分泌干扰物的基础上,从通过与核受体结合的基因作用及非基因信号通路作用方面阐述了环境内分泌干扰物的作用机制,并探讨了环境内分泌干扰物对母婴健康的影响,包括对母亲的影响及对胎儿、婴儿的影响方面。同时强调应重视其对激素水平不稳定的孕期母体及敏感初期生命的影响。

On the basis of an overview of environmental endocrine disruptors, the action mechanism of environmental endocrine disruptors is introduced from the aspects of gene function with nuclear receptor and non-gene signaling pathway. The effect of environmental endocrine disruptors on maternal and child health is also discussed, including the effects on mother, fetus n and infant. Meanwhile, it also emphasizes that the effect of environmental endocrine disrupto~ on mother with unstable hormone levels and sensitive early life should be paid great attention.