丙泊酚复合七氟醚用于小儿腹股沟疝修补术的效果观察

EFFECTS OF PROPOFOL COMBINED SEVOFLURANE IN INGUINAL HERNIA REPAIR OF CHILDREN

目的:探讨丙泊酚复合七氟醚麻醉在小儿腹股沟疝修补术中的临床效果。方法:40例1-10岁的腹股沟疝修补手术患儿,随机分为丙泊酚复合七氟醚麻醉组(A组)和丙泊酚静脉组(B组),每组20例患儿。观察两组患儿给药后血流动力学的变化、自主呼吸恢复时间、术后苏醒时间和麻醉后不良反应。结果:B组气管插管后即刻(M1)、插管后1min(M2)、切皮时(M3)、手术开始后15min(M4)、手术开始后30min(M5)的MAP、HR明显高于诱导前(M0)(P<0.05),且明显高于A组同时间点;A组不同时间点MAP、HR、RR、SpO2、PETCO2比较差异无统计学意义(P>0.05)。A组自主呼吸恢复时间、术后苏醒时间短于B组,差异具有统计学意义(P<0.05)。两组均无插管反应,且术后均无明显不良反应。结论:丙泊酚复合七氟醚吸入麻醉可安全应用于小儿腹股沟疝修补术,是一种较有效的麻醉方法,且无明显不良反应及并发症,有利于术后恢复。

Objective：To investigate the clinical effects of propofol combined sevoflurane in anaesthesia of children inguinal hernia repair surgery.Methods：40 cases aged 1-10 inguinal hernia repair children were randomly divided into 2 groups（n=20）： propofol combined sevoflurane anaesthesia group（group A） and propofol anaesthesia group（group B）.The hemodynamic indexes of children after anaesthesia,spontaneous recovery time,recovery time and adverse reactions were observed.Results：The MAP and HR of children in group B immediately after tracheal intubation,1min after tracheal intubation,skin incision,15min after beginning of operation and 30min after beginning of operation were all obviously higher than that before induction of anaesthesia（P0.05）;Moreover,obviously higher than that of children in group A at same time point（P0.05）.There had no obvious differences about MAP,HR,RR,SpO2 and PETCO2 of children in group A between different time point（P0.05）.The spontaneous recovery time and recovery time of children in group A were significantly shorter than that of children in group B（P0.05）.Group A and group B all had no intubation reaction and obvious adverse reactions.Conclusions：Propofol combined sevoflurane in children inguinal hernia repair surgery is safe,effective and beneficial of postoperative recovery;Moreover,no obvious adverse reactions.