地佐辛复合左布比卡因颈丛麻醉用于甲状腺手术的临床观察

Clinical observation of dezocine compounded levobupivacaine cervical plexus anesthesia on thyroid surgery

目的观察地佐辛复合左布比卡因颈丛神经阻滞用于甲状腺手术的效果。方法 2010年4月-2012年5月择期行甲状腺肿瘤切除的患者60例,随机分成地佐辛复合左布比卡因麻醉组(Ⅰ组)和单用左布比卡因组(Ⅱ组),每组30例。观察感觉阻滞起效时间、镇痛质量、对心血管系统的影响及治疗用药情况和术后镇痛情况。结果Ⅱ组HR、MAP与Ⅰ组比较差异有统计学意义(P<0.05或P<0.01),Ⅱ组与Ⅰ组比较,麻醉镇静、镇痛、手术满意度等均低于Ⅰ组,两组比较差异有统计学意义(P<0.01)。结论地佐辛复合左布比卡因颈丛神经阻滞在甲状腺手术中镇痛和镇静效果更明显,安全可控性好,对颈丛麻醉下甲状腺手术时的心血管反应有显著的抑制作用。

Objective To observe the clinical efficacy of dezocine compounded levobupivacaine cervical plexus anesthesia on thyroid surgery.Methods 60 patients needing thyroid tumor resection from April 2010 to May 2012 were randomly divided into dezocine compounded bupivacaine anesthesia group（group Ⅰ） and levobupivacaine group（group Ⅱ）,30 patients in each group.To observe the sensory block onset time,analgesia quality,impact on the cardiovascular system,drug uses and postoperative analgesia.Results Compared with group,HR,MAP of groupⅡ had significant difference（P0.05 or P0.01）,Postoperative analgesia and surgical satisfaction of groupⅡwere lower than those of group Ⅰ（P0.01）.Conclusion Dezocine compounded levobupivacaine cervical plexus block using for thyroid surgery has better analgesic and sedative effect,it is safe and has good controllability and significant inhibition effect on the cardiovascular responses of cervical plexus anesthesia.