摘要
“卫生学假说”可能是导致近年来儿童哮喘发病率增加的原因,大量的临床试验表明在消化系统疾病方面起着积极作用的益生菌制剂能够预防和治疗儿童特应性皮炎、食物过敏,但对预防、治疗哮喘的结论不一,越来越多的动物实验显示了益生菌在哮喘的预防或治疗方面的积极作用,其机制仍在探索中,以乳酸杆菌为代表的益生菌制剂在未来可能为儿童哮喘的临床防治提供新的思路。
"Hygiene hypothesis" may be the reason for the increased incidence of childhood asthma in recent years. A large number of clinical studies indicate that, probiotics, which play a positive role in the digestive system diseases, can prevent and treat children atopic dermatitis as well as food allergies, but the conclusions of prevention and treatment of asthma have been inconsistent. More and more of the animal experiments show that probiotics have benefical effects in the prevention or therapy of asthma,its mechanism is still in the exploration, probiotics such as lactobacillus will provide a new clinical thought for the prevention and treatment of childhood asthma in the future.
出处
《国际儿科学杂志》
2012年第6期545-548,553,共5页
International Journal of Pediatrics
关键词
哮喘
益生菌
预防
治疗
Asthma
Probiotics
Prevention
Treatment