IL-17及其受体与肺炎支原体感染

IL-17, IL-17 receptor and mycoplasma pneumoniae infection

随着对支原体肺炎发病机制研究的不断深入，动态观察细胞因子变化对判断肺炎支原体（MP）感染有一定指导意义。研究显示MP感染与白细胞介素（IL）-17及其受体密切相关，两者可能共同参与中性粒细胞的招募，参与抗MP感染的免疫反应。该文就IL-17及其受体与MP感染的关系进行综述。

With the development of mycoplasma pneumonia （MP） pathogenesis research, the dynamic observation of changes of cytokines on judgement of the infection of mycoplasma is of certain guiding signifi- cance. Domestic and foreign studies showed that MP infection was Closely related with IL-17 and its receptor. IL-17 and its receptor may be involved in neutrophil recruitment, and in resistance to MP infection on the immune response, In this paper, the relationship between IL-17and its recepter and mycoplasma infection are reviewed.