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抽吸导管联合替罗非班治疗对急性STEAMI患者冠脉无复流的影响 被引量:1

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摘要 目的观察在急性ST段抬高型心肌梗死(STEAMI)的急诊介入治疗(PCI)中使用冠脉内血栓抽吸导管联合盐酸替罗非班治疗对发生冠脉无复流的影响。方法选择2010年1月至2011年12月急诊入院的急性STEAMI患者共96例,在进行急诊冠状动脉造影结束后,按照就诊顺序分为冠脉内血栓抽吸导管联合盐酸替罗非班治疗的PCI治疗组(研究组)及单纯PCI治疗组(对照组),观察比较两组PCI术后冠状动脉的心肌梗死溶栓试验(TIMI)血流情况。结果研究组患者PCI术后TIMI血流3级100.0%;单纯PCI组患者术后TIMI血流3级75.0%,TIMI血流0~2级25.0%;两组比较差异有统计学意义(P<0.05)。两组患者术后肌酸激酶(CK)及肌酸激酶同工酶(CK-MB)的变化以及术后1周左心室射血分数LVEF值比较,差异均有统计学意义(P<0.05)。术后随访2个月两组患者均无主要心血管事件(MACE)发生。结论在急性STEAMI的急诊PCI治疗中,使用冠脉内血栓抽吸导管联合盐酸替罗非班治疗可明显减少患者PCI术后梗死相关冠脉的无复流现象的发生,明显改善急性心肌梗死患者的预后。
出处 《内科》 2012年第6期600-602,共3页 Internal Medicine
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