类风湿性关节炎血清学指标与腕关节动态增强MRI表现的相关性分析

Correlation Analysis of Serological Markers with Wrist Dynamic Contrast-enhanced MRI Findings in Rheumatoid Arthritis

目的:探讨类风湿性关节炎(RA)血清学检查指标与腕关节滑膜动态增强MRI表现之间的相关性。方法:对经临床诊断为RA的26例患者的腕关节动态增强MRI和血清学检查资料进行总结,根据MRI上腕关节滑膜动态增强表现不同来分组,比较血清学指标(CRP、IgA、IgG和IgM值)之间有无差异性。结果:26例腕关节MRI均显示有滑膜增厚,其动态增强曲线类型包括快升平台型14例和慢升型12例。快升平台型患者的血清CRP值高于慢升型患者的CRP值(P<0.05),两种动态增强曲线类型之间三种免疫球蛋白值的差异无统计学意义(P>0.05)。结论:血清CRP值与腕关节滑膜MRI动态增强曲线类型相关,而血清IgA、IgG和IgM值与动态增强MRI曲线类型无关。

Objective ： To investigate the correlation of serological markers with wrist dynamic contrast-enhanced MRI findings in rheumatoid arthritis （ RA ）. Method ： The data of wrist dynamic contrast-enhanced MRI and serological examinations were reviewed in 26 cases of clinically diagnosed RA patients. The difference of the value of serological markers, including CRP, IgA, IgG and IgM, was compared in the patients with different dynamic enhanced MRI findings of the wrist synovium. Result ： The wrist MRI showed the synovial thickening in 26 cases. The dynamic contrast- enhanced MR1 curve types included fast-increasement- platform type （ 14 eases ） and slow-inereasement type （ 12 cases ） . The CRP value in the fast- increasement- platform curve type garoup was significantly higher than that in the slow-lncreasement type garoup （ P〈0.05 ） . There were no significant differences of IgA, IgG and IgM values between the fast-lncreasementplatform curve type garoup and the slow-lncreasement type garoup （ P〉0.05 ） . Conclusion ： The serum CRP levels are associated with wrist synovial dynamic contrast-enhanced MRI curve types, however, the serum IgA, IgG and IgM values have no correlation with wrist synovial dynamic enhanced MRI curve types.