丙泊酚复合布托啡诺在无痛人工流产术中的应用观察

To Observe the Application of Propofol Combined with Butorphanol on Painless Artificial Abortion Operation

目的:对丙泊酚复合布托啡诺在无痛人工流产术中的应用进行对照观察,为人工流产术的临床麻醉提供个体化依据。方法:在丙泊酚复合布托啡诺麻醉下行人工流产术的156例患者作为观察组,同期在丙泊酚麻醉下的132例患者作为对照组,观察两组患者丙泊酚用量和患者的苏醒时间,同时观察两组患者术中恶心呕吐和呼吸抑制的发生情况。结果:两组患者在丙泊酚用量和患者的苏醒时间方面比较差异均有统计学意义(P<0.01)。两组患者恶心发生率比较差异有统计学意义(P<0.01),呕吐发生率比较差异无统计学意义(P>0.05);两组患者术中呼吸暂停的发生率比较差异有统计学意义(P<0.01)。结论:无痛人工流产术中,丙泊酚复合布托啡诺可以减少丙泊酚的使用剂量,缩短患者的苏醒时间,患者术中恶心感和呼吸暂停发生率较低。

Objective：Contrast observation of the application of propofol combined with butorphanol on painless artificial abortion operation, to provide the individual basis for clinical anesthesia of artificial abortion operation.Method ： 156 cases who were used with propofol and butorphanol on artificial abortion operation as observe group , and 132 cases who just used with propofol as control group, observed the dosage of propofol and awakening time of two group patients, meanwhile, observed nausea and vomiting and respiratory depression of two group patients.Result ： The difference of the dosage of propofol and awakening time between the two groups patients had statistical significances （ P〈0.01 ） .The difference of the rate of nausea between the two groups patients had statistical significances （ P〈0.01 ）, but the difference of the rate of vomiting had no statistical significances （ P〉0.05 ） ; the rate of respiratory depression of two group patients had statistical significances （ P〈0.01 ） .Concluslon：The application of propofol combined with butorphanol on painless artificial abortion operation can reduce the dosage of propofol, and shorten the patients＇ awakening time, the rate of nausea and respiratory depression are lower.