多巴胺能神经递质及受体显像的临床研究和应用进展

Development of clinical study and application on dopaminergic neurotransmitters and neuroreceptor imaging

近年来神经递质显像发展极快 ,已从大量的基础研究进入临床应用的研究。目前中枢神经递质显像中以多巴胺能神经递质及受体显像最为活跃 ,主要包括多巴胺受体、多巴胺能神经元神经递质和多巴胺转运蛋白显像等。PET和 SPECT核医学功能影像技术对各种神经精神疾患、运动性疾病的诊断和鉴别诊断以及开展认知功能研究具有独特优势。

In recent years, the neurotransmitter mapping has been rapidly developed from a lot of fundamental researches to the studies of clinical applications. At present, the dopaminergic neurotransmitter and receptor imaging in the central neurotransmitter mapping study are the most active area including dopaminergic receptor, dopaminergic neurotransmitter and dopaminergic transporter imaging, etc,. The nuclear medicine functional imaging technique with positron emission tomography and single photon emission computed tomography possesses potential advantages in the diagnosis and distinguished diagnosis of neuropsychiatric disorders and movement disorders, and in the study of recognition function.