注射用重组人生长激素治疗胸部创伤所致心肌挫伤的疗效观察

Clinical observation of recombinant human growth hormone for treating myocardial contusion

目的:观察重组人生长激素(Recombinant human growth hormone,rhGH)治疗胸部创伤所致心肌挫伤的疗效。方法:将55例胸部创伤所致心肌挫伤患者随机分为对照组27例和治疗组28例。对照组采用常规吸氧、严密监护常等治疗手段,治疗组在此基础上连续皮下注射rhGH 15 d后观察疗效。结果:经过rhGH的治疗,治疗组磷酸肌酸同工酶(CK-MB)、肌钙蛋白I(cTnI)、肌钙蛋白T(cTnT)改善情况明显好于对照组(P<0.05),心律失常率10.7%和心肌缺血率14.3%情况明显好于对照组的33.3%和37.0%(P<0.05)。结论:重组人生长激素对胸部创伤所致心肌挫伤具有治疗作用,可以进一步推广。

Objective To observe the clinical effect of treating myocardial contusion with recombinant human growth hormone.Methods 55 patients were randomly divided into a experiment group（28 cases） and a control group（27 cases）.The control group were treated with conventional treatment such as oxygen and intensive care,while the experiment group were treated with recombinant human growth hormone additionally for 15 days.Results After rhGH treatment,the treatment group（CK-MB）,phosphocreatine isozymes of troponin l（cTnl）,cardiac troponin T（cTnT） to improve the situation significantly better than the control group（P 〈 0.05）,arrhythmia and myocardial ischemia was 10.7% rate of 14.3% was obviously better than the control group of 33.3% and 37%（P 〈 0.05）.Conclusion Treating myocardial contusion with recombinant human growth hormone has clinical therapeutic effect.