肺切除早期肺循环血液动力学改变及其临床意义

Early phase change of pulmonary hemodynamics and clinical signicant after lung resection

目的 :为了解肺叶切除术术后肺循环血液动力学改变 ,更好地做好围手术期的处理。方法 :行动物试验 ,以右心导管直测肺切除前、后的肺动脉压、心排量等的变化 ,临床上对 46例肺切除病理应用无创性多普勒超声技术检测术前、后的肺循环血液动力学有关指标。结果 :肺切除术后经上述两种方法所测结果 :肺动脉平均压升高 ,心排量下降 ,肺血管阻力上升。与肺切除前所测值对比 ,经统计学处理P <0 0 1。结论

Objective:The purpose of investigate the changes of pulmonary hymodynamics after lung resection and affers a better postoperative management.Methods:Cardiac catheterization was employed to determines data of pulmonary artery mean pressure and cardiac putout on pre-operation in dog.The 46 patients were studied who accepted the lung resection and adopts 2-D and Doppler echocardiagraphy to determines data of pulmonary hemodynamics.Results:The results show that pulmonary artery mean pressure and total pulmonary resistance elevatedand cardiac output decreased after lung resection comparing with those before operation the difference significant(P< 0.01 ).Conclusion:pulmonary hemodyna mics was harmed after lung resection.It is importants to take note of perioperative treatment. [