摘要
肠道内数以亿计的微生物及其代谢产物在人体能量代谢、营养物质吸收、先天和获得性免疫、胃肠道功能等方面发挥着重要作用,一旦宿主与肠道微生物之间共栖共生的稳态被打破,就会诱发多种人类疾病。目前已经认识到肠道微生物与人类健康和疾病的密切关系,仅仅从人类自身角度出发来研究人类疾病远远不够,必须考虑到与人类共栖共生的肠道微生物的作用。本文就近年来有关肠道微生物与人类疾病关系研究的进展进行综述。
The majority of human intestinal microbiota are harmless or even beneficial by performing functions essential for our survival. Changes in the microbial species that reside in our intestines have been associated with a long list of illness. The review provided an overview of the association between the microbiota and the occurrence of human diseases~ and to stimulate future researches regarding infectious diseases and their consequences.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2012年第12期1168-1176,共9页
Medical Journal of Chinese People's Liberation Army
关键词
遗传学
微生物
下胃肠道
基因组学
genetics, microbial
lower gastrointestinal tract
genomics
