摘要
目的 观察前列腺素E1治疗病毒性肝炎高胆红素血症的疗效。方法 2 35例病毒性肝炎高胆红素血症病人随机分为治疗组 12 0例 ,对照组 115例。两组均采用相同的基础疗法。治疗组加用前列腺素E12 0 0 μg加入 10 %葡萄糖5 0 0ml中 ,缓慢静脉滴注 ,每天 1次。疗程 4周或TBil正常后停用。结果 治疗组总有效率为 89.2 % ,对照组为 73 %。两组相比差异有显著性意义 (P <0 .0 5 )。治疗组在降酶、退黄及缩短肝功能复常时间方面明显优于对照组 (P <0 .0 1)。结论 前列腺素E1治疗病毒性肝炎高胆红素血症疗效确切 。
Objective To study the effect of PGE 1 on hyperbilirubinemia caused by viral hepatitis.Method 235 patients with hyperbilirubinemia caused by viral hepatits were randomly divided into two groups.They both received the same conventional therapy.In addition to the conventional therapy,120 cases in treatment group were treated with PGE 1(200μg),added to 500ml of glucose injection,given by intraveous drip,once per day.The course of treatment ended when the serum biliburin reached the normal values or did not exceed 4 weeks at most.Results In the treatment group the total effective rate was 89.2%,while in the control group 73%.There was significant difference between the two group( P <0.05).The treatment group was significantly superior to the control group in reducing ALT and TBil( P <0.01).Conclusion PGE 1 may be effective in treating hyperbilirubinemia caused by viral hepatitis and the regimen can be applied in hospital of all levels.
出处
《现代诊断与治疗》
CAS
2000年第4期206-208,共3页
Modern Diagnosis and Treatment
