3Wong J, Hoe NW, Zhiwei F, et al. Apoptosis and traumatic brain injury [J]. Neurocrit Care, 2005, 3(2):177-182.
4Springer JE, Nottingham SA, MeEwen ML, et al. Caspase-3 apoptotic signaling following injury to the central nervous system [J]. Clin Chem Lab Med, 2001, 39(4):299-307.
5Juan TS, McNiece IK, Jenkins NA, et al. Molecular characterization of mouse and rat CPP32 beta gene encoding a eysteine protease resembling interleukin-1 beta converting enzyme and CED-3 [J]. Oncogene, 1996, 13(4) :749-755.
6Conti AC, Raghapathi R, Trojanowski JQ, et al. Experimental brain injury induces regionally distinct apoptosis during the acute and delay post- traumatic period [J]. J Neurosci, 1998, 18(15):5663-5672.
7Riggs JE. Delayed diffuse neurodegeneration after cerebral concussion [J]. Mil ned, 2001, 166(11):1029-1030.
8Bakshi A, Keck CA, Koshkin VS, et al. Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain [J]. Brain Res, 2005, 1065(1/2):8-19.
9Cao G, Pei W, Lan J, et al. Caspase-activated DNase/DNA fragmentation factor 40 mediates apoptotic DNA fraonentation in transient cerebral ischemia and in neuronal cultures [J]. J Neurosei, 2001, 21 (13) :4678-4690.
10Springer JE, Nottingham SA, McEwen ML, et al. Caspase-3 apoptotic signaling following injury to the central nervous system [J]. Clin Chem Lab Med, 2001, 39(4):299-307.
1Garelick MG, Kermedy BK. TOR on the brain [ J]. Exp Gerontol, 2011, 46 (2/3): 155-163.
2Yang H, Rudge DG, Koos JD, et al. mTOR kinase structure, mechanism and regulation [ J ]. Nature, 2013, 497 (7448) : 217-223.
3Hoeffer CA, Klann E. mTOR signaling: at the crossroads of plasti- city, memory and disease [ J]. Trends Neurosci, 2010, 33 (2) : 67-75.
4Chong ZZ, Shang YC, Wang S, et al. A critical kinase cascade in neurological disorders: PI3-K, Akt, and mTOR [J]. Future Neurol, 2012, 7 (6): 733-748.
5DoMing R J, Topisirovic I, Fonseca BD, et al. Dissecting the role of mTOR: Lessons from mTOR inhibitors [ J ]. Biochim Biophys Acta, 2010, 1804 (3): 433439.
6Dazert E, Hall MN. roTOR signaling in disease[J]. Curr Opin Cell Biol, 2011, 23 (6) : 744-755.
7Cota D.mTORC2, the "other" mTOR, is a new player in energy balance regulation [J]. Mol Metab, 2014, 3 (4): 349-350.
8Maiese K. Cutting through the complexities of mTOR for the treat- ment of stroke [J]. CurrNeurovasc Res, 2014, 11 (2) : 177- 186.
9Pastor MD, Garcia-Ybenes I, Fradejas N, et al. mTOR,/S6 kinase pathway contributes to astrocyte survival during ischemia[J]. J Siol Chem, 2009, 284 (33): 22067-22078.
10Zare Mehrjerdi F, Aboutaleb N, Habibey R, et al. Increased phosphorylation of mTOR is involved in remote ischemicpreconditioning of hippocampus in mice [ J]. Brain Res, 2013, 1526: 94-101.
