52例睫状体占位性病变的组织来源、临床特征及组织病理学分析

The histogenesis, clinical features and histopathological analysis on 52 cases of ciliary body neoplasms

目的 分析睫状体部占位性病变的组织来源和类型、临床表现、鉴别诊断特点以及组织病理学特征 ,为临床提供诊断和治疗依据。方法 对存档的 5 2例睫状体组织标本 ,根据其解剖部位、组织来源进行系统的临床特征及组织病理学分析。结果 5 2例组织标本按解剖部位分类 :位于睫状体病变 38例 (73 1% ) ,原发于睫状体累及虹膜组织 14例 (2 6 9% ) ;按组织来源分类 :占第 1位者为睫状体神经上皮来源的肿瘤 2 0例 (38 5 % ) ,第 2位者为恶性黑色素瘤 14例 (2 6 9% ) ,第 3和第 4位者分别为黑色素细胞瘤 9例 (17 3% )和肉芽肿性炎性病变 5例 (9 6 % )。结论 对睫状体肿物临床特征和组织病理学特点的分析 。

Objective To analyze the histogenesis, classification, incidence, clinical feature, the key point of differential diagnosis and histopathologic characteristics of ciliary body neoplasms to provide the basis for clinical diagnosis and treatment Method 52 specimens of ciliary body neoplasms on file were analyzed and studied for the characteristics of clinical presentation and histopathology Results Of the 52 specimens, 38 were located in the ciliary body (73.1%), and 14 lesions involved the iris (26.9%). According to the results of histogenetic classification, the tumors of ciliary sensory epithelium were ranked the first place (20 cases, 38.5%) while malignant melanoma, the second one (14 cases, 26.9%) followed by melanocytoma (9 cases, 17.3%) and granulomatous lesions (5 cases, 9.6%). Conclusion The clinical features and histopathologic characteristics of ciliary body neoplasms are systemically and deeply recognized, that may help clinical ophthalmologists to make correct diagnosis and proper treatment