鼻咽癌筛查成本效果的初步分析

Cost-effectiveness of screening of nasopharyngeal carcinoma

目的:评价鼻咽癌新筛查方案的成本和效果。方法:在鼻咽癌高发区中山市进行鼻咽癌筛查,统计癌检出率、早诊率、人均筛查成本、发现早期病例平均费用和早期发现成本系数等指标。结果:共筛查16 712人,确诊鼻咽癌25例,检出率149.59/10万,早诊率76.0%,治疗率100.0%。筛查成本41.56元/人,发现病例费用27 779.82元,发现早期病例费用36 552.40元,按我国人均GDP计算,早期发现成本系数(EDCI)为1.71,按中山市人均GDP计算,EDCI为0.65。结论:相对常见恶性肿瘤鼻咽癌筛查成本较高,但在高发区筛查可以显著提高早诊率,并降低治疗费用。

OBJECTIVE： To evaluate the cost effective of the new screening program for nasopharyngeal carcinoma （NPC） patients. METHODS： A new screening program was used in Zhongshan City with a high incidence for NPC. The effect was measured by using the cancer detection rate, early diagnosis rate, the cost per screening, the average early detec- tion cost and the early detection cost index （EDCD. RESULTS： Totally 16 712 adults were recruited to the study with in- formed consent and 25 NPC cases were detected. The cancer detection rate was 149.59 per 100 000. The rate of early de- tection was 76.0K and these patient could be completely cured. The cost per screening was ￥41.56,and the detection cost was ￥27 779.82. The early detection cost was ￥36 552.40 and EDCI was 1.71 with the country GDP and 0.65 with the Zhongshan City GDP. CONCLUSION： Although the screening cost for NPC is higher than that for other canc- ers. The early diagnosis rate can be significantly improved which results an effective treatment.