扶正涤痰化瘀法治疗血管性痴呆68例临床观察

Clinical Observation on 68 Cases with Vascular Dementia Treated by Strengthening the Body Resistance and Removing Phlegm and Blood Stasis

目的 :观察扶正涤痰化瘀法治疗血管性痴呆的临床疗效。方法 :采用国际诊断标准 ,观察组 68例用扶正涤痰化瘀法治疗 ;对照组 38例用尼莫地平、喜得镇、阿斯匹林治疗 ,疗程 60天。结果 :观察组临床控制 4例 ,显效 1 8例 ,有效 38例 ,无效 8例 ;对照组临床控制 1例 ,显效 6例 ,有效 1 7例 ,无效 1 4例 ;两组疗效比较 ,有显著性差异 (P <0 .0 5)。 2组治疗后MMSE积分增加变化比较 ,有非常显著性差异 (P <0 .0 1 ) 。扶正涤痰化瘀法尚有降低血粘度作用 (治疗前后自身比较P <0 .0 1 )。结论

Purpose: To observe the clinical effect on vascular dementia treated by strengthening the body resistance and removing phlegm and blood stasis. Methods: After the diagnosis based on the international diagnostic standards, the 68 cases in the observation group were treated in the light of TCM theory of strengthening the body resistance and removing phlegm and blood stasis. The 38 cases in the control group on the other hand were treated with Nimodipine, Hydergine and Aspirin. The treatment course was 60days. Results: In the observation group, the total effective rate amounted to 88.24%, with 4 cases in the clinical control, 18 with the remarkable effective rate, 8 with the effective rate and 8 with the ineffective rate. However in the control group, the total effective rate reached only 63.16%, with 1 case in the clinical control, 6 with the obvious effective rate, 17 with the effective rate and 14 with the ineffective rate. Also a very significant difference was indicated in the change and increase of the integral of mini-mental state examination between the two groups after the treatment (P< 0.01). The therapy employed in the observation group could lower the blood viscosity when the self-comparison was made before and after the treatment (P<0.01). Conclusions: By using the therapy of strengthening the body resistance and removing phlegm and blood stasis, better curative effects can be achieved for the patient with vascular dementia.