高频超声结合彩色多普勒对溃疡性结肠炎活动性的判定价值

Color Doppler ultrasonography in assessment of activity of ulcerative colitis

使用高频超声结合彩色多普勒对60例溃疡性结肠炎（UC）进行检查，以Sourtherland评分指数（DAI）作为UC患者活动期判断标准，总结活动期患者声像图及血流信号特点。结果显示，UC患者活动期超声表现为肠壁增厚、层次改变或消失、肠壁血流信号增多。超声评价疾病活动期的准确性为85．0％，敏感性为90．0％，与临床评分一致性较好（P〈0．01）。提示，UC患者活动期的超声表现具有一定特点，结合彩色多普勒对疾病活动性的判定准确性、敏感性较高，可作为病情随访及药物疗效的观察指标的参考依据。

Sixty patients with ulcerative colitis （UC）, including 28 males and 32 females were enrolled in the study. Color Doppler uhrasonographic scans were performed and the disease activity was estimated base on the Sourtherland score index （DAI）. On the sonography the colon with active inflammatory disease showed bowel wall thickening, alteration of layers structure or even discrimination and increased vascular signals. Using DAI as the gold standard, the sensitivity, specificity, positive predictive value, negative predictive value and accurate rate for ultrasonography in assessment of UC activity were 90. 0% （36/40） ,75.0% （15/20）, 87.8% （36/41）, 78.9% （ 15/19）, 85.0% （51/60）, respectively. In conclusion, Color Doppler ultrasonography provides a convenient technique for assessment of bowel involvement and inflammatory activity in ulcerative colitis with high sensitivity and accuracy.