烯二炔类抗肿瘤抗生素全合成研究.含芳环烯二炔单元开链衍生物的合成

Total Synthesis of Enediyne Antitumor Antibiotics Ⅳ. Synthesis of Acyclic Derivatives Containing Aromatic Ring Enediyne Unit

以 2 -溴苯甲醛为原料 ,经 6步反应 ,得到含芳环十元环状烯二炔单元开链衍生物。共合成 12个新化合物 ,其结构均经1

Acyclic derivatives of enediyne units were prepared from 2 bromobenzaldehyde through six steps. Twelve new compounds were obtained and their structures, were elucidated with 1HNMR and MS.