期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

新型二氮杂二环化合物的制备、拆分及生物活性研究

Synthesis,Resolution and Biological Activity of Novel Diazabicyclo Compound
下载PDF
导出
摘要 以1,3-丙二胺与乙酰丙酸为原料反应得二氮杂二环,然后加入缚酸剂NaOH与二氯乙酰氯一锅法反应制备了5-二氯乙酰基-6-甲基-9-氧杂-1,5-二氮杂二环[4.3.0]壬烷,采用红外光谱、氢核磁、碳核磁进行了表征,并对所合成物质进行了拆分,采用室内生物测定法研究了外消旋体及其光学异构体在土壤中豆磺隆残留时对玉米的保护效果。 A novel diazabicyclo compound 5 - dichloroacetyl - 6 - methyl - 9 - oxo - 1, 5 - diazabicyclo [ 4.3.0 ] nonane was synthesized with 1, 3 -propanediamine, acetylpropionicacid and dichloroacetyl chloride. The compound was characterized by IR, ^1H NMR and ^13 C NMR. Resolution of this compound with L - （ ＋ ） - tartaric acid was also carried out. The preliminary biological test showed that the compounds protected maize against injure by chlorimuron to some ex-tent.
作者 李颖娇 刘玉琛 马静 李立国 李理
机构地区 东北农业大学理学院应用化学系
出处 《广州化工》 CAS 2012年第23期42-44,共3页 GuangZhou Chemical Industry
基金 黑龙江省教育厅项目(No.11541036)
关键词 除草剂安全剂 二氮杂二环 制备 拆分 生物活性测定 herbicide safener diazabicyclo synthesis resolution biological activity
分类号 O626.29 [理学—有机化学]
  • 相关文献

参考文献10

  • 1李颖娇,叶非.除草剂安全剂对作物细胞色素P450及其他酶活性和水平的影响[J].农药学学报,2003,5(3):9-15. 被引量：18
  • 2李淑琴,赵景兴,王金会,杨明生,刘晓英.氯嘧磺隆在豆田使用技术研究[J].农药,1998,37(8):32-33. 被引量：6
  • 3Streck H. J. Fate of chlorsufuron in the environment [ J ]. Pestic Sci, 1998,53( 1 ) :29 -51.
  • 4Devlin R. M. ,Zbiec I. I. Effect of BAS - 145138 as an antidote for sul- fonylurea herbicides [ J ]. Weed Technol. , 1990,4 ( 2 ) : 337 - 340.
  • 5Fuerst E. P. , Lamoureax G. L. Mode of action of dichloroaeetamide an- tidote BAS - 145138 in corn II. effects on metabolism, absorption, and mobility of metazachlor. Pestic. Biochem. Physiol. ,1992,42: 78-87.
  • 6Herbert S. , et al. Preparation of(R) -5 -dichloroacetyl- 3,3,6 -tri- methyl - 9 - oxo - 1,5 - diazabieyelo [ 4.3.0 ] Nonane as a herbicide safeners. Ger. Often. DE 3609003, 1987 -6 -16.
  • 7刘汉标,汪波,季凤英,许遵乐.光活性胺的合成和拆分[J].中山大学学报（自然科学版）,1996,35(5):73-76. 被引量：1
  • 8白国义,陈立功,邢鹏,李阳,闫喜龙.乙胺丁醇的合成[J].精细化工,2004,21(12):943-945. 被引量：17
  • 9Gronwald J. W. , Fuerst E. P. , Eberlein C. V. , et al. Effect of herbi- cide antidotes on glutathione content and glutathione S -transferase ac- tivity of sorghum shoots [ J ] . Pestic Biochem and Physio1,987,29 (1) : 66 - 76.
  • 10Devlin R. M. , Zbiec I.I. Effect of four safeners against the herbicidal activity of V -53482 in corn( Zea mays). Plant growth regulator society of America quarterly, 1993, 21 (4) :190 - 197.

二级参考文献40

  • 1Milhomme H, Roux C, Bastide J. Safeners as corn seedling protectants against acetolactate synthase inhibitors[J. Z Naturforschung, 1991,46 (c) : 945-949.
  • 2Nemat Alla M M, Hassan N M. Efficacy of branched-chain amino acids and naphthalic anhydride for soybean protection from rimsulfuron toxicity[J]. Egyptian Journal of Botany, 2000,38 : 1-2,205-221.
  • 3Frear D S, Swanson H R, Mansager E R. 1, 8-Naphthalic anhydride/auxin protection against chlorsulfuron inhibition of corn seedling growth[A]. Greenhalgh,R, Roberts T R. Pesticide Science and Biotechnology [C]. Oxford.. Blackwell, 1987. 499-503.
  • 4Fuerst E P, Lamoureax G L,Ahrens W H. Mode of action of dichloroacetamide antidote BAS145-138 in corn I . Effects on metabolism, absorption, and mobility of metazachlor[J]. Pestic Biochem Physiol,1992, 42: 78-87.
  • 5Wu J R, Omokawa H, Hatzios K K. Glutathione S-transferase activity in unsafened and fenclorimsafened rice (Oryza sativa)[J]. Pesticide Biochemistry and Physiology(USA), 1996, 54(3):220-229.
  • 6Cottingham C K, Hatzios K K, Meredith S. Influence of chemical treatments on glutathione S-transferases of maize with activity towards metolachlor and cinnamic acid [J]. Zeitschrift fur Naturforschung Section C Biosciences, 1998, 53:11-12, 973-979.
  • 7Alla M M N, Hassan N M. Efficacy of exogenous GA3 and herbicide safeners in protection of Zea mays from metolachlor toxicity[J]. Plant Physiology and Biochemistry Paris, 1998, 36 : 11, 809-815.
  • 8Andrews C, Skipsey M, Edwards R, et al. Changes in glutathione transferase activities in soybean in response to trearment woth herbicides and safeners [A]. Brighton Crop Prot Conf-Weeds [C].Brighton :British Crop Prot Council, 1997, 2 : 825-830 .
  • 9Nemat A M M. The influence of naphthalic anhydride and 1-aminobenzotriazole on maize tolerance to herbicides: a possible role for glutathione S-transferase in herbicide persistence and detoxification[J].Agricoltura Mediterranea , 2000, 130:1,18-26.
  • 10Kunkel D L, Steffens J C, Bellinder R R. Effect of temperature and safeners on glutathione levels and glutathione-S-transferase activity in maize[J]. Z Naturforschung, 1991,46:856-860.

共引文献37

广州化工
2012年 第23期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部