表阿霉素和顺铂介入治疗晚期卵巢癌

Exploration of interventional treatment with Epiadiamyein/Cisplatin in advanced ovarian cancer

探讨晚期卵巢癌的介入治疗方法及疗效。方法 :对 13例晚期卵巢癌在 DSA下行表阿霉素和顺铂介入治疗并观察疗效、手术切除率及毒副反应。结果 :近期有效率 84.6 % ,对腹水的客观有效率为10 0 .0 % ,手术切除率 80 .0 %。随访 :经 7～ 2 5个月 (平均 16 .5月 )随访 ,13例中 6例无癌存在 ,5例仍在治疗中 ,2例死亡。结论 :表阿霉素 (EPI)、顺铂 (DDP)介入治疗卵巢癌效果显著 ,但术后应辅以 6～ 10个疗程静脉化疗。

Objective:To evaluate interventional approach and efficasy of Epiadiamycin(EPI)/Cisplatin(DDP)regimen for women with advanced ovarian cancer.Methods:Thirteen patients with advanced ovarian cancer,of whom,ten with stage Ⅲ,one stage IV,two with relapsing cancer,were treated by EPI/DDP arterial infusion.The response,excision rate,toxicity and side effects were assessed after treatment.Results:Short term effective rate is 84.6%. objective effective rate of ascites relieving is 100%.Excision rate is 80%.Follow up visits from 7 to 25 months average 16.5m were made.6 cases survived without cancer,5 still receiving treatmeat and 2 cases died.Conclusion:EPI/DDP arterial infusion therapy is an effective treatment for ovarian cancer with little side effect and toxicity.But it is important that patients be given 6～10 courses of adjuvant chemotherapy after operation.