乙型肝炎胃粘膜病变与胃幽门螺杆菌感染的相关性研究

Correlation between helicobacter pylori infection and gastric mucosal change in hepatitis B patients

探讨乙型肝炎患儿胃内幽门螺杆菌 (HP)感染的相关性。方法 :受筛选后儿童 35 2人 ,胃镜观察胃十二指肠粘膜病变的程度 ,并利用粘膜活检快速尿素酶试验测定 HP的感染率。结果 :乙型肝炎患儿112例 HP感染率为 75 .0 % ,而对照组 2 40例 HP感染率为 45 .9% ,两者之间差异有显著性 (P<0 .0 1)。结论 :研究结果表明 ,乙型肝炎与 HP感染之间高度相关。

Objective:To study the correlation between hepatitis B and Helicobacter pylori (Hp) infection.Methods:Endoscopy was performed in 352 screened children to observe gastroduodenal nucosal change and the prevalence of Helicobacter pylori infection was determined by the urease rapid test from mucosal biopsies.Results:The prevalence of Helicobacter pylori infection was 75.0% in 112 cases of hepatitis B patients, which was significantly higher than 45.9%in 240 cases of control (P<0.01).Conclusion:It is suggested that there is significant correlation between hepatitis B and Helicobacter pylori infection.