阻塞性肺疾病并睡眠呼吸暂停综合征的相关因素分析

Analysis of Chronic Obstructive Pulmonary Disease with Obstructive Sleep Apnea Syndromes

目的 :探讨肺心病并睡眠呼吸暂停综合征的相互影响。方法 :对 2 4例肺心病并睡眠呼吸暂停综合征患者的临床资料进行回顾性分析 ,并与 2 1例肺心病组对比观察。结果 :两组 1s用力呼出气量 (FEV1)、用力呼气峰流量 (PEFR)均有统计学意义的降低 ,血气分析比较PaO2 降低 ,PaCO2 升高 ,有显著性差异 (P <0 0 5) ,pH降低无显著性差异。结论 :阻塞性肺心病并阻塞性睡眠呼吸暂停综合征加重低氧血症、高碳酸血症 。

Objective:To study the influences between chronic obstructive pulmonary disease(COPD)with obstructive sleep apnea syndrome(OSAS).Method:The clinical data of 24 cases of COPD with OSAS were retrospectively analyzed,compared with the control(21s with COPD).Results:FEV1 and PEFR of groups were decreased singnificantly,PaO 2 of blood gas analysis was descreased,and PaCO 2 increased (P<0 05) .Conclusion:COPD with OSAS could worsen the hypoxemia,and affected obviously lung function.