温莪术化学成分的研究

Studies on Chemical Constituents of Curcuma aromatica Salisb.

目的 :对温莪术药用有效成分进行研究。方法 :采用溶剂提取 ,D 10 1大孔吸附树脂柱粗分 ,硅胶柱及薄层色谱进行分离纯化 ,物理、化学和波谱学方法鉴定化合物的结构。结果 :分离得 5个化合物 ,莪二酮、新莪二酮、莪术醇、四甲基吡嗪、(R) (+) 1,2 十六烷二醇。结论 :新莪二酮 2和 (R) (+) 1,2 十六烷二醇为首次从温莪术中分离获得 ,后者为姜黄属植物中首次报道 ,并优化了上述其它化合物的分离纯化方法。

Objective:To study the effective ingredients of Curcuma aromatica .Method:Solvent extraction was used.The constituents were isolated with resin D 101 silica gel column and thin layer chromatography,and the structures were elucidated by physico chemical properties and spectral analysis.Result:Curdione,neocurdione,curcumol,tetramethylpyrazine and ( R ) (+) 1,2 hexadecanediol were isolated from C. aromatica .Conclusion:Neocurdione and ( R ) (+) 1,2 hexadecanediol were isolated from C. aromatica for the first time,and was isolated from Curcuma and reported for the first time. [