白细胞介素与支架内再狭窄

Interleukins and in-stent restenosis

支架置入术后的支架内再狭窄是困扰动脉粥样硬化性心脑血管病微侵袭介入治疗发展的主要问题。支架置入术后的血管内炎症反应是再狭窄的重要原因之一。其中，以白细胞介素为代表的细胞因子起着复杂和多变的作用。文章综述了白细胞介素表达水平对血管内皮增生的作用以及对支架内再狭窄发生率的影响。

In-stent restenosis after stenting is a major problem to perplex the minimaJly invasive interventional treatment and development in atherosclerotic cardio-cerebrovascular diseases. Intravascular inflammatory response is one of the important causes for restenosis after stenting, in which as represented by interleukins, the cytokines play complex and variable roles. This article reviews the effects of the expression levels of interleukins on vascular endothelial hyperplasia and the incidence of in-stent restenosis.