儿童再发性呕吐临床治疗分析

Children with recurrent vomiting clinical analysis

目的探讨儿童再发性呕吐临床治疗效果。方法 2008年6月至2011年6月收治的符合入选标准儿童再发性呕吐病例60例为常规组32例,治疗组28例观察两组临床疗效。结果两组临床近期疗效治疗组总有效率92.85%,常规组总有效率65.62%,经统计学分析,两组总有效率比较有显著差异性(P<0.01)。结论发病率约为儿童3.15/10万,是继胃食管反流造成儿童反复呕吐的第二病因;本病反复频繁发作,发作形式刻板,具有突发突止特性,任何年龄阶段儿童均可发病<5岁的儿童多发,无显著性别差异;典型症状为突然出现反复剧烈恶心、呕吐,发作可以持续数小时到数天,同时伴有自主神经全身症状如轻度血压增高、多汗、流涎、发热、面色苍白、嗜睡、乏力等;神经系统症状可以出现头痛、眩晕、畏声、畏光等。急性期应用胞二磷胆碱及连续应用多虑平、赛庚啶可以显著缩短儿童再发性呕吐急性发作期,减少复发。

Objective To investigate the children＇s clinical treatment of recurrent vomiting.Methods From June 2008 to June 2011 met the inclusion criteria of children admitted to recurrent vomiting 60 cases for the conventional group of 32 patients,the treatment group,28 cases of clinical efficacy.Results The clinical curative effect treatment group the total effective rate was 92.85%,the total efficiency of the conventional group 65.62%,the statistical analysis,the total effective rate had significant differences（P0.01）.Conclusion The incidence rate is about children 3.15/10 million,is the second cause of cause children repeated vomiting following gastroesophageal reflux;repeated frequent attacks of the disease,seizures rigid form,has burst suddenly ended characteristics,children of any age can children 5 years of age of onset of multiple,no significant gender differences;typical symptoms of the sudden appearance of repeated severe nausea,vomiting,seizures can last for a few hours to a few days,accompanied by autonomic nervous systemic symptoms such as mild hypertension,hyperhidrosis,salivation,fever,pale,drowsiness,fatigue,etc;nervous system symptoms,headache,dizziness,phonophobia,photophobia.The acute phase of citicoline and continuous application of doxepin,cyproheptadine can significantly shorten children with recurrent vomiting,acute exacerbation of reducing recurrence.