摘要
目的:讨论N-乙酰半胱氨酸治疗特发性肺间质纤维化(IPF)的疗效。方法:将40例患者随机分为实验组和对照组,试验组在常规糖皮质激素治疗的基础上加用N-乙酰半胱氨酸600mg,3次/日,疗程12个月,观察两组的临床症状和肺功能。结果:对照组试验组的临床症状和肺功能有统计学意义。结论:对于IPF患者,在强的松标准治疗方案基础上加用N-乙酰半胱氨酸可以有效地改善IPF的症状和肺功能。
Objective：To discuss whether acetylcysteine are effective in the treatment of patients with idiopathic pulmonary fibrosis.Methods：40 cases were randomly divided into the research group and the control group,The basis of glucoco rticoids treatment and the acetylcysteine were used on the research group.The clinical features and the lung function were measured inpatientsoftwogroups.Results：There was no difference on the demographic data and variables at baseline between two groups.Compared with the control group,the clinical features and the lung function had significantly improved in the research group.Conclusions：Acetykysteine would be effective and safe for the treatment of idiopathic pulmonary fibrosis.
