摘要
缩聚合成聚醚醚酮,与纳米羟基磷灰石混合,制成聚醚醚酮/羟基磷灰石生物复合材料,用热重分析法研究其热稳定性.研究表明,该材料热分解起始温度在500℃以上,热稳定性好;升温速率对热重曲线有重要影响,随着升温速率加快,热失重曲线向高温区平移,起始分解温度和最大热分解速率温度提高,反应临近结束的拐点温度也提高;随着羟基磷灰石含量的增大,该复合材料的最大分解速率逐渐降低,热稳定性优于聚醚醚酮.细胞毒性试验显示,该复合材料对Hela细胞无明显毒性,对细胞生长有促进作用,生物相容性良好.
Based on the polycondensation of polyetheretherketone, by adding hydroxyapatite blended into （polyetheretherketone, PEEK）, biological composite materials were prepared. Thermogravimetric analysis was conducted to study the thermal stability of the composite materials. Results show that the thermal decomposition temperatures are above 500 ℃ in the beginning, showing desirable thermal stability. Heating rates have an important influence on thermogravimetric curves. Further, as heatings speed up, thermogravimetric curves move to a high temperature, and the initial decomposition temperature and maximum thermal decomposition temperature increase. Also, maximum decomposition rate decreases with the increase of HA content, indicating that the thermal stability of PEEK/HA composites are better than that of PEEK. A cytotoxicity test shows that PEEK/HA composites have no significant toxicity to Hela cells, and they promote cell growth, showing that the biological compatibility of PEEK/HA composites is good.
出处
《深圳大学学报（理工版）》
EI
CAS
北大核心
2012年第6期521-526,共6页
Journal of Shenzhen University(Science and Engineering)
基金
国家自然科学基金资助项目(50878131)
深圳大学应用技术开发项目(201223)~~
关键词
复合材料
聚醚醚酮
热稳定性
分解动力学
细胞毒性
生物相容性
composites
polyetheretherketone
thermal stability
decomposition kinetics
cytotoxicity
biological compatibility
