摘要
目的:通过对ICU院感脓毒症患者病原菌检测、耐药性及预后分析,为临床合理用药和控制院感提供科学依据。方法:回顾性分析206例ICU院感脓毒症患者的临床资料。结果:感染者以有基础性疾病的老年人、长期用药、病情危重、接受侵入性检查与治疗的患者居多;感染部位以呼吸道、泌尿道、导管相关性疾病感染为最多见;共分离病原菌394株,常见病原菌主要是G-杆菌190株(铜绿假单胞菌为主),其次是G+球菌118株(金黄色葡萄球菌为主)、真菌86株(白色假丝酵母菌为主);常见病原菌耐药性较高;预后主要影响因素是重视并加强临床护理及心血管、呼吸、泌尿、血液、消化、神经等多系统、多脏器功能障碍等。经临床综合治疗,采取有效预防和护理措施,改善预后。结论:由于ICU院感脓毒症患者常见病原菌耐药性较高,应根据药敏试验结果合理用药;有效预防和护理措施及心血管、呼吸、泌尿、血液、消化、神经等多系统、多脏器功能障碍等是影响其预后主要因素,临床应积极防治并加强护理,改善预后。
Objective:To detect the pathogen,analyze the drug resistance and prognosis situation in patients with nosocomial sepsis in ICU and provide scientific basis for clinical drug use.Methods: Clinical information of 206 patients with sepsis in ICU was carried out retrospective analysis.Results: Most infectors were elder patients with basic diseases and patients undertaken long-term administration,critical diseases,invasive examination and treatment.Most infection sites were respiratory tract,urinary tract and catheter-related infection.394 pathogens were isolated from 206 patients.The common pathogens were mainly 190 gram negative(G-) bacteria,followed by 118 G+ cocci and 86 fungi strains.Common pathogens had high resistance.The main prognostic factors were clinical care and dysfunction of cardiovascular,respiratory,urinary tract,blood,digestive and neural systems.Conclusion: Due to the high drug resistance of common pathogens,rational drug use should be based on drug sensitive test results.Effective prevention and care measures and cardiovascular,respiratory,urinary,digestive,nervous,blood and multiple organ dysfunction are the main factors affecting the prognosis.
出处
《中国卫生检验杂志》
北大核心
2012年第11期2771-2773,2776,共4页
Chinese Journal of Health Laboratory Technology
基金
温州市科技计划项目(Y20090249)