摘要
The self-assembly of the precatalyst modules, which are amino acids and cinchona alkaloid derivatives, leads to the direct formation of the desired organocatalysts without any synthesis. These modularly designed organocatalysts （MDOs） may be used for catalyzed asymmetric aldol reaction the corresponding aldol products may be obtained in mediocre diastereoselectivities （up to 79 ： 21 dr）. Depending on structure of the aldehyde substrates, to excellent ee values （up to 92% ee） with moderate
The self-assembly of the precatalyst modules, which are amino acids and cinchona alkaloid derivatives, leads to the direct formation of the desired organocatalysts without any synthesis. These modularly designed organocatalysts （MDOs） may be used for catalyzed asymmetric aldol reaction the corresponding aldol products may be obtained in mediocre diastereoselectivities （up to 79 ： 21 dr）. Depending on structure of the aldehyde substrates, to excellent ee values （up to 92% ee） with moderate
