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Organocatalytic Asymmetric Branching Sequence of MBH Carbonates: Access to Chiral Benzofuran-2(3H)-one Derivatives with Three Stereocenters 被引量:1

Organocatalytic Asymmetric Branching Sequence of MBH Carbonates: Access to Chiral Benzofuran-2(3H)-one Derivatives with Three Stereocenters
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摘要 An organocatalytic asymmetric branching sequence was realized in the presence of 10 mol% of (DHQD)2AQN, affording the sequential products with three stereocentres, including two quaternary carbon centres, in 47%-79% yields with 85%-99% ee. An organocatalytic asymmetric branching sequence was realized in the presence of 10 mol% of (DHQD)2AQN, affording the sequential products with three stereocentres, including two quaternary carbon centres, in 47%-79% yields with 85%-99% ee.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2012年第11期2693-2702,共10页 中国化学(英文版)
基金 Acknowledgement This work was supported financially by the National Natural Science Foundation of China (Nos. 20972110 and 20902067).
关键词 ORGANOCATALYSIS Morita-Baylis-Hillman (MBH) carbonates chloroaldoximes branching sequences enantioselectivity organocatalysis, Morita-Baylis-Hillman (MBH) carbonates, chloroaldoximes, branching sequences,enantioselectivity
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