哮喘发作期儿童与成人不同肺功能表现的分析

Analysis about the Differences in Pulmonary Function Performance between Children and Adults with Asthma in Acute Exacerbation

目的探讨哮喘发作期儿童与成人不同肺功能表现.方法采用肺功能仪测定哮喘发作期儿童与成人呼吸生理参数.结果 (1)成人与儿童在哮喘发作期时其FEV1、PEF、FEF25、FEF50、FEF75、MMEF指标均为敏感性指标,成人MVV及FEV1%仍属敏感指标,而在儿童却不敏感;(2)哮喘发作期儿童用力呼气时间(FET)明显较成人短(P<0.05);(3)儿童以限制性通气功能为主,成人以阻塞性通气功能障碍为主.结论儿童呼气时间短以及潮气量小造成哮喘发作期通气功能以限制性障碍为主.

Objective To explore the differences in pulmonary function performance between children and adults with asthma in acute exacerbation.Methods JAEGER Master Screen Diffusion determinator was used to determine respiratory physiologic parameters respectively both in children and adults with asthma in acute exacerbation.Results（1）FEV1,PEF,FEF25,FEF50,FEF75 and MMEF were the sensitive indicators for children and adults.MVV and FEV1% are the sensitive indicators for adults,but not for children.（2）The children＇s FET was quite shorter than the adult＇s during acute exacerbation of asthma（P〈0.05）.（3）Children were mainly with restrictive ventilation function obstacle,while adults were mainly with obstructive ventilation function obstacle.Conclusion The short expiration time and little tidal volume make the restrictive ventilation function obstacle mainly occur in children with asthma in acute exacerbation.