钬激光与气压弹道碎石术治疗肾结石的临床疗效比较

Comparison of Clinical Efficacy between Holmium Laser and Pneumatic Ballistic Lithotripsy in Treatment of Kidney Stones

目的比较钬激光与气压弹道碎石术治疗肾结石的临床方法及效果.方法 2011年5月至2012年3月收集的88例肾结石患者随机分为研究组和对照组,研究组44例患者采用钬激光碎石手术,对照组44例患者采用气压弹道碎石手术.观察和记录患者手术时间、术中出血量、碎石率、结石排净时间、临床并发症、平均住院时间等组间比较.结果 2组在手术时都具有较好的治疗有效性和安全性,气压弹道碎石术术中出血量为(88.2±2.3)mL,并发症发生率为11.36%,钬激光碎石术术中出血量为(62.8±2.0)mL,并发症发生率为4.55%,显著低于气压弹道碎石术(P<0.05);同时钬激光碎石术可缩短住院时间(P<0.05);手术时间无差异(P>0.05).结论钬激光碎石手术与气压弹道碎石手术相比治疗肾结石具有更好的有效性和安全性,可减少术中出血量和并发症发生率,缩短住院时间.

Objective To compare the clinical methods and effects between holmium laser and pneumatic ballistic lithotripsy in treatment of kidney stone.Methods 88 patients with kidney stones from may 2011 to March 2012 were divided into2 groups：studygroup and control group.The 44 patients in studygroup were given holmium laser lithotripsy,44 patients in contral group got pneumatic ballistic lithotripsy.We observed the patient operation time,intraoperative amount of bleeding,gravel rate,stones exhaust net time,clinical complications,the average hospitalization time and compared them between groups.Results The two groups in the operation had better therapeutic efficacy and safety,for pneumatic ballistic lithotripsy intraoperative,the amount of bleeding was（88.2 ±2.3）,complication rate was 11.36%,for the holmium laser lithotripsy intraoperative the amount of bleeding was（62.8±2.0） mL,complication rate was 4.55%,which were significantly lower than pneumatic ballistic lithotripsy（P〈0.05）;Holmium laser lithotripsy shortened hospitalization time（P〈0.05）,but had no change in operation time（P〈0.05）.Conclusion Compared with pneumatic ballistic lithotripsy,holmium laser lithotripsy in treatment of kidney stone has better efficacy and safety,can reduce the amount of bleeding and intraoperative complications,and shorten hospital stay.