脱氧核苷酸钠联合舒肝宁注射液治疗肝损害的临床疗效观察

Clinical efficacy of deoxyribonucleotide natrium combined with Shuganning injection in the treatment of liver damage

目的观察脱氧核苷酸钠联合舒肝宁注射液治疗肝损害的疗效,为临床用药提供参考。方法选择肝损害患者90例,随机分为两组,均给予静脉注射脱氧核苷酸钠,观察组患者在此基础上给予静脉注射舒肝宁。观察治疗前后两组患者肝功能指标的变化,并比较治疗期间两组患者不良反应发生率的差异。结果经治疗后,两组患者肝功能等指标均较治疗前有所下降,与对照组比较,观察组改善程度明显较大。两组不良反应发生率比较,差异无统计学意义。结论采用脱氧核苷酸钠联合舒肝宁注射液治疗肝损害疗效确切,且不会增加不良反应,值得推广应用。

Objective To observe the clinical efficacy of deoxyribonucleotide natrium with Shuganning injection in the treatment of liver damage, provide reference for clinical. Methods 90 cases with liver damage were selected and divided into two groups randomly, the control group and the observation group, both of the two groups were given deoxyribonucleotide natrium injection. Based on this, the observation group was also given Shuganning injection. Observed the changes of AST, ALT,GGT and TBIL before and after the treatment. And compared the adverse reactions incidence of the two groups. Results After the treatment, the AST, ALT, GGT and TBIL indicators of the two groups had declined. Compared with the control group, the observation group had been improved significantly largely. The adverse events of the two groups had no statistically significant. Conclusion It has exact effect of deoxyribonucleotide natrium with Shuganning injection in the treatment of liver damage, without increasing adverse reactions, it is worthy for clinical.