抗结核药物不良反应110例的临床分析

Clinical analysis on 110 cases of adverse reaction caused by anti-TB drugs

目的探析应用抗结核药物导致的不良反应的特点。方法选择笔者所在医院2009年1月～2011年6月应用诊断为肺结核病的患者110例,应用抗结核药物治疗的,并对治疗过程中出现的不良反应情况进行总结。结果应用抗结核药物所致的不良反应以胃肠道反应最高,其次是肝功能损害、过敏反应、肾功能损害和神经损害,所有患者经对症治疗后均治愈。结论应用抗结核药物治疗的过程中应密切关注患者病情,以及时发现不良反应,并给与相应的治疗,及时调整治疗方案,以免给患者带来不必要的痛苦。

Objective To investigate the anti-TB drugs leads to adverse characteristics.Methods 110 cases are the author＇s hospital from January 2009 to June 2011 Application diagnosed with TB patients,to summarize the adverse events in the course of treatment.Results The adverse reactions caused by the application of anti-TB drugs to the gastrointestinal tract reaction,followed by liver damage,allergic reactions,renal dysfunction and neurological impairment,all patients with symptomatic treatment were cured.Conclusion The application of anti-TB drug treatment process should pay close attention to the patients＇ condition,and found that adverse reactions,and appropriate treatment,timely adjustment of the treatment program,so as not to cause unnecessary suffering to the patients.