定痛汤结合中医体质学说治疗痛风性关节炎的临床研究

Clinical study of the Dingtong decoction and constitution theory of TCM in gouty arthritis

目的观察定痛汤合白芍总苷胶囊治疗痛风性关节炎的临床疗效。方法将96例痛风性关节炎患者随机分为治疗组48例,对照组48例。两组患者均给予基础治疗。治疗组每日予定痛汤合白芍总苷胶囊口服,对照组给予美洛昔康片治疗。1个疗程后治疗结束前后观察两组患者生化检查指标及安全性指标。结果临床疗效:治疗组总有效率为95.74%。对照组总有效率为91.30%。组间疗效比较,差异无统计学意义(P>0.05)。治疗前后两组生化检查组内比较,差异有统计学意义(P<0.05)。安全性分析:全部患者治疗前后检查血尿常规及肝肾功能均无异常改变。结论定痛汤合白芍总苷胶囊治疗痛风性关节炎能显著提高临床疗效,缩短病程,改善痛风性关节炎伴随症状,且有较好的安全性。

Objective To observe the clinical effect of Dingtong decoction and Total glucosides of paeony capsules in gouty arthritis. Methods We investigated 96 patients with gouty arthritis and divided them into two group,the experimental group（48） and control group（48）.Both group were treated by basic treatment. the experimental group were treated with psychological nursing Dingtong decoction and Total glucosides of paeony capsules.The control group were treated with Meloxicam Tablets.After a course of treatment,we investigated the biochemical index and symptom score and safety index. Results The total effective rate of experimental group was 95.74%,and the control group was 91.30%,and the differences was not statically significant（P 0.05）.There was a remarkable differencein biochemical index （P 0.05）.and after the treatment,the blood routine urine routine and the hepatic and renal function of the patients had no abnormal change. Conclusion The clinical effect of Dingtong decoction and Total glucosides of paeony capsules in gouty arthritis could significantly improve the clinical efficacy,concomitant symptom and shorten the course, and it is safety.