胸段食管癌淋巴结转移与临床病理因素的相关性

Lymph node metastasis of thoracic esophageal carcinoma correlation with clinicopathological factors

目的探讨胸段食管癌淋巴结转移规律以及影响淋巴结转移的因素。方法对笔者所在医院2010年5月～2012年3月收治的108例胸段食管癌患者进行手术治疗的术后病理进行回顾分析,探讨胸段食管癌淋巴结转移规律以及影响淋巴结转移的因素。结果 108例胸段食管癌患者,淋巴结的总转移率是53.4%,通过对术后病理的观察分析,P<0.05,OR值>1,表明浸润深度、肿瘤长度、分化程度是淋巴结转移的独立危险因素,这3个因素和胸段食管癌淋巴结转移之间存在关联性。结论胸段食管癌淋巴结转移的主要规律是:由患者的颈部胸部和腹部向淋巴的引流区域进行转移,最常见的转移区域就是纵隔,然后是患者的腹部和颈部;影响淋巴结转移的因素主要是肿瘤的长度、肿瘤浸润的深度以及分化的程度。

Objective To investigate the lymph node metastasis of thoracic esophageal carcinoma rule and influence factors related to lymph node metastasis. Methods 108 cases of thoracic esophageal carcinoma patients undergoing operation in treatment of postoperative pathology in our hospital from May 2010 to March 2012 were analyzed retrospectively. Esophageal carcinoma lymph node metastasis and the impact of factors related to lymph node metastasis were investigated. Results 108 cases of thoracic esophageal cancer patients,lymph node transfer rate was 53.4%,through the postoperative pathological observation and analysis,P 〈 0.05,OR values 〉1,indicated the depth of invasion,tumor length,degree of differentiation were independent risk factors of lymphatic metastasis. Conclusion The lymph node metastasis of thoracic esophageal carcinoma：the main rule is composed of patients with neck thorax and abdomen to lymph drainage area is transferred,the most common metastatic area is the mediastinum,then is the patient＇s abdomen and neck;the impact of lymph node metastasis are the main factor in tumor length,tumor invasion depth and the degree of differentiation.