准分子激光原位角膜磨镶术矫正成人屈光性弱视的临床疗效与安全性

The efficacy and safety of excimer laser in situ keratomileusis ablation to improve visual acuity in adults with refractive amblyopia

目的分析准分子激光原位角膜磨镶(近视矫正)术对成人框架镜最佳矫正视力(BSCVA)不能纠正的屈光性弱视患者的视力影响。方法调查2011年11月至2012年2月期间在我院眼科门诊术前行框架镜最佳矫正视力无法纠正的高度近视合并散光的成人弱视患者(n=26),在接受准分子激光近视矫正术的术前与术后视觉恢复情况。结果接受准分子激光手术前患者裸眼视力平均为(0.19±0.09)(范围:0.1～0.40),术前BSCVA平均为(0.68±0.12)(范围:0.30～0.50),二者比较有统计学差异(P<0.05);术后1个月与6个月复查裸眼视力分别为(0.92±0.15)和(0.97±0.07),与术前裸眼视力及BSCVA值比较,差异显著(P<0.05)。结论准分子激光近视矫正术可以矫正部分高度近视合并散光(框架镜最佳矫正视力无法矫正)的成人屈光性弱视。

Objective To analyze the effect of laser in situ kemtomileusis to correct high myopic astigmatism in patients with suboptimal best spectacle-corrected visual acuity （ BSCVA）. Methods Twenty-six eyes of consecutive pa- tients with suboptimal BSCVA and high myopic astigmatism of 3 diopters or more were intervened by excimer laser in situ keratomilensis surgery, and main outcome measures with NV. Results The mean of naked visual acuity （ NV ） in preoperative period is （ 0.19 ± 0.09 ） （ range, 0.10 to 0.40 ） , and the mean of BSCVA before surgery is （ 0.68 ± 0.12） （ range, 0.30 to 0.50） in all patients. Compared with preoperative NV and BSCVA, the NV is improved significantly after surgery （ 1 month after surgery：0. 92 ± 0. 15, 6 months after surgery： 0. 97 ± 0. 07） （ P 〈 0. 05 ）. Conclusions h eyes with high myopic astigmatism and suboptimal preoperative BSCVA, excimer laser in situ keratomileusis may result in a significant im- provement in NV.