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蠕虫免疫调节分子的抗炎作用与机制 被引量：1

Anti-inflammatory Effect and Mechanism of Immunomodulators of Helminthes
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摘要 新近研究发现,一些蠕虫来源的免疫调节分子可预防或治疗小鼠模型中多种自身免疫性疾病和过敏性反应。本文综述了多种蠕虫来源的免疫调节分子及其在小鼠模型中的抗炎效应和作用机制。 Recent studies indicate that many helminth-derived products can prevent or treat a variety of autoimmune diseases or allergy in mice models. This review summarizes research advances on helminth-derived immunnomodulators, and discusses the anti-inflammatory effect and possible mechanisms in mice model.
作者 汪雪峰 杜久伟
机构地区 安徽理工大学医学院医学检验教研室
出处 《中国寄生虫学与寄生虫病杂志》 CAS CSCD 北大核心 2012年第6期486-490,共5页 Chinese Journal of Parasitology and Parasitic Diseases
基金 国家自然科学基金(No.30801046) 安徽省学术与技术带头人后备人选科研项目 安徽理工大学硕博基金(No.2010YB004) 安徽理工大学中青年骨干资助~~
关键词 蠕虫 免疫调节分子 抗炎作用 Helminth Immunomodulatory molecule Anti-inflammatory effects
分类号 R186 [医药卫生—流行病学]
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参考文献45

  • 1Okada H, Kuhn C, Feillet H, et al. The 'hygiene hypothesis' for autoimmune and allergic diseases: an update [J]. Clin Exp Immunol, 2010, 160(1): 1-9.
  • 2van Riet E, Hartgers FC, Yazdanbakhsh M. Chronic helminth infections induce immunomodulation: consequences and mechanisms[J]. Immunobiology, 2007, 212(6): 475-490.
  • 3Cooke A. Review series on helminths, immune modulation and the hygiene hypothesis: how might infection modulate the onset of type 1 diabetes?[J]. Immunology, 2009, 126(1): 12-17.
  • 4Carvalho L, Sun J, Kane C, et al. Review series on helminthes, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function [J]. Immunology, 2009, 126(1) : 28-34.
  • 5van der Kleij D, Latz E, Brouwers JF, et al. A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like receptor 2 and affects immune polarization [J]. J Biol Chem, 2002, 277(50): 48122-48129.
  • 6Ham DA, McDonald J, Atochina O, et al. Modulation of host immune responses by helminth glycans[J]. Immunol Rev, 2009, 230(1) : 247-257.
  • 7Aksoy E, Zouain CS, Vanhoutte F, et al. Double-stranded RNAs from the helminth parasite Schistosoma activate TLR3 in dendritic cells[J]. J Biol Chem, 2005, 280(1): 277-283.
  • 8van Riet E, Everts B, Retra K, et al. Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 Dolarization[J]. BMC Immunol, 2009, 10: 9.
  • 9Goodridge HS, Marshall FA, Else KJ, et al. Immunomodulation via novel use of TLR4 by the filarial nematode phosphoryl- choline-containing secreted product, ES-62 [J]. J Immunol, 2005, 174(1): 284-293.
  • 10Melendez AJ, Harnett M, Pushparaj PN, et al. Inhibition of FeeR Ⅰ-mediated mast eell responses by ES-62, a produet of parasitic filarial nematodes [J]. Nature Med, 2007, 13(11): 1375-1381.

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中国寄生虫学与寄生虫病杂志
2012年 第6期

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