子宫内膜干细胞及其与血管生成关系的研究进展

Endometrial Stem Cells and Their Relationship with Angiogenesis

大量的临床观察和基础研究均提示,子宫内膜中存在一些干细胞,它们具有高度增殖、自我更新和的分化潜能。目前有学者研究子宫内膜干细胞是否可能成为子宫内膜病变患者进行内膜修复替代治疗的手段,以及是否可以在毛细血管重建及血管发生中发挥作用。虽然近年来在子宫内膜干细胞的鉴定和分离方面有了很大的进展,但对于它的特异性标志物仍在探索中。同时对子宫内膜干细胞的研究可为内膜异位症、子宫内膜癌等疾病的治疗提供新的思路。本文针对国内外研究者近年来在这发面的研究现状进行综述。

A lot of clinical observation and basic research suggest that endometrial exist stem cells with high proliferation, self-renewal and differentiation potential. Although in recent years, research on endometrial stem ceil isolation and identification has made great progress, but the endometrial stem cell specific markers are still in exploration. Endometrial stem cells may become the new way for patients who have endometrial lesions to make use of endometrial repair replacement therapy means, and provide a new research thought for endometriosis, endomelrial cancer. At present, scholars research whether endometrial stem cells play a role in capillaries reconstruction and angiogenesis. This paper gave a review on the resent research at home and abroad.