雷公藤红素抗肿瘤作用研究进展

Research Progress on the Anti-tumor Effect of Celastrol

雷公藤红素是中药雷公藤的一个单体成分,在体内外均具有较强的抗肿瘤活性。研究表明雷公藤红素具有抑制肿瘤细胞转移,以及抑制血管内皮细胞生长等作用。作者查阅了近年来国内外的文献,对雷公藤红素的抗肿瘤作用进行综述,为雷公藤红素的抗肿瘤研究提供依据。

Celastrol is a compound of Tripterygium wilfordii Hook. f, which has strong anti-tumor activity in vitro and in vivo. Research has shown celastrol can inhibit tumor metastasis and angiogenesis, and induce apoptosis of turnout cells. According to a large number of domestic and international studies on Celastrol in recent years, anti-tumor effects of Celastrol were reviewed, so as to provide a basis for the anti-tumor research of Celastrol.