COPD患者肺部感染控制窗的影响因素分析

Pulmonary Infection Control Window Factor Analysis in Patients with Chronic Obstructive Pulmonary Disease

目的探讨COPD患者肺部感染控制窗(PIC窗)的影响因素及临床意义。方法对68例早出现PIC窗的患者和62例晚出现PIC窗的患者进行调查,判定PIC窗的影响因素。结果 COPD患者的较早出现PIC窗组为(3.6±0.8)d,较晚出现PIC窗组为(7.8±0.6)d,两组差异有统计学意义(P<0.001);Logistic多因素回归分析结果为雾化吸入支气管舒张剂(P=0.006)和床旁支气管镜吸痰(P=0.001)是主要影响因素;结论雾化吸入支气管舒张剂和床旁支气管镜吸痰治疗有利于COPD患者PIC窗提早出现,把握好PIC窗,有助于危重症COPD急性加重期的治疗。

Objective To investigate the chronic obstructive pulmonary disease （COPD） patients with pulmonary infection control window （PIC window） influencing factors and clinical significance. Methods Determine the impact factors of PIC window were investigated retrospectively 68 cases of patients with early emergence of PIC window and 62 cases of patients with late PIC window to univariate analysis and logistic regression analysis. Results The difference was statistically significant （ P 〈 0. 001 ）, COPD patients earlier PIC window group （3.6 ±0. 8） d and a late PIC window group （7.8 ±0.6） d; The atomization inhaled bronchodilators （P =0. 006）, and bedside bronchoscopic suctioning （P =0. 001 ） is the main influencing factors, by Logistic multivariate regression analysis; Conclusions Atomization of inhaled bronchodilators and bedside bronchoscopy suction treatment in patients with chronic obstructive pulmonary disease PIC window appeared earlier; control PIC window will help critically ill patients with acute exacerbation of COPD phase of treatment.