妊娠期高血压疾病危险因素及对母婴预后的影响

Risk factors of hypertensive disorder complicating pregnancy and its effect on pregnancy outcome

目的探讨妊娠期高血压疾病的相关危险因素及其对母婴结局的影响。方法选择2011年1月～2012年6月在我院进行产检并确诊为妊娠期高血压疾病的孕产妇136例为高血压组,选择同时期在我院进行产检的健康孕产妇130例为对照组。对其各主要生化指标、社会人口学特征等情况进行调查分析比较。结果年龄≥35岁或年龄≤20岁、文化程度低、体重指数、双胎妊娠、孕产妇母亲有高血压病史、每天做家务时间较长、没有补充叶酸等均为高危因素。四组间TG、TC、HDL-C、FIB、LDH比较差异均有统计学意义(P<0.01)。各组分娩孕周及新生儿体重比较差异有统计学意义(P<0.01)。结论妊娠期高血压疾病与诸多因素有关,了解其高危因素,积极预防高血压的发生,从而改善孕产妇及围生儿的结局。

Objective To discuss the risk factors of hypertensive disorder complicating pregnancy and its effect on preg- nancy outcome. Methods Collected 136 cases with hypertensive disorder complicating pregnancy in Jan 2011-Jun 2012, and 130 healthy pregnant women were selected at the same time. Biochemical criterion and demographic features were an- alyzed. Results Age over 35 years old or less than 20 years old, ill-educated, high-BMI, gemellary pregnancy, mother with hypertension, puting in long hours at home, without taking folic acid were risk factors of hypertensive disorder complicating pregnancy. TG, TC, HDL-C, FIB, LDH in four groups had significant difference （P 〈 0.01 ）. The gestational age and birth weight in four groups had significant difference（P 〈 0.01 ）. Conclusion There are many risk factors of hypertensive disorder complicating pregnancy. To know these risk factors and to prevent hypertensive disorder can improve pregnancy outcome.