CCCHP和CHP治疗恶性积液的疗效对比观察

The contrast observation of using CCCHP and CHP in treatment of malignant effusion

目的对体腔恒温循环热灌注化疗(CCCHP)和体腔热灌注化疗(CHP)疗效进行比较。方法把130例恶性积液分别行CCCHP和CHP治疗,观察其疗效和毒副反应,分析两种方法出入体腔液体不同时间段的温差。结果CCCHP组CR+PR率为86%,CR率为31.6%,高于CHP组的CR+PR率为57.5%,CR率为17.8%,差异有统计学意义(P<0.05);出体腔液体温度变化两组有差异,且时间段越长差异越显著。结论 CCCHP能保证体腔内的有效治疗温度,在治疗恶性积液的疗效上有明显提高。

Objective The therapeutic efficacy of using CCCHP and CHP to treat malignant effusion is compared in this essay. Methods The author observed the efficacy and toxic reaction of using CCCHP and CHP to treat the 130 cases of malignant effusions and analyzed the liquid＇s differences in temperature when using the two methods togo through the, body cavity at different times. Results The RR rate of the CCCHP group （86%） was noticeably higher than that of the＇ CHP group （57.5%）. The CR rate of the CCCHP group （31.6%） was noticeably higher than that of the CHP group （17.8%）. The differences were statistically significant. There were differences in temperature of going out of the body cavity and the longer the time period was, the more noticeable difference can be got. Conclusion CCCHP can ensure the temperature of the effective treatment within the cavity, and the therapeutic efficacy of treating malignant effusions is noticeably improved.