新生儿血糖水平与缺氧缺血性脑病脑损害相关性研究

Research of neonatal blood glucose level of correlation with hypoxic -ischemic encephalopathy brain damage

目的分析研究新生儿血糖水平与发生缺氧缺血性脑病脑损害之间的相关性。方法将我院2011年5月～2012年4月收治的HIE患儿40例根据血糖水平分为正常组与低血糖组，各20例。对患儿进行血糖监测，动态观察低血糖组与正常血糖组患儿的脑损害症状消失的时间并对其进行Gesell法智能评分。结果低血糖组症状消失的平均时间显著高于正常组（P〈0．05）；此外，低血糖组的Gesell法智能评分显著低于正常组患儿（P〈0．05）。结论低血糖可加重HIE脑损害，及时纠正低血糖可减轻HIE脑损害的程度，降低脑瘫的发病率。

Objective To analyze the neonatal blood glucose level with the correlation between the occurrence of hypoxie- isehemie eneephalopathy brain damage. Methods In our hospital from May 2011 to April 2012, 40 cases with HIE were divided into normal group and hypoglycemia group, according to the blood sugar levels ,each group had 20 cases. To moni- toring blood glucose of children, and dynamically observe the time of children＇s brain damage symptoms disappeared and its Gesell Act smart rated. Results The average time of symptoms disappearing of the hypoglycemia group was significantly higher than the normal group（P 〈 0.05）. In addition ,the Gesell Act Smart Ratings of hypoglycemia group was significant- ly lower than the normal group （P 〈 0.05）. Conclusion Low blood sugar can aggravate HIE brain damage, and promptly correct the hypoglycemia can reduce the degree of HIE brain damage and also reduce the incidence of cerebral palsy.